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Our latest paper is now available to view on bioRxiv



Our latest paper, in which we identify pericytes as metabolic sentinels of the brain is now available in preprint through bioRxiv. Congratulations to Ashwini for great efforts in leading this project! 

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Abby is selected to join the Training Program in Integrative Membrane Biology


New publication in Science Advances


Our new paper reveals that capillaries in the brain control blood flow branch-by-branch through the capillary bed using an elaborate array of calcium signals. We estimate that there are over a million of these events every second throughout the mouse cortex. See the press release here.

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A huge congratulations to Abby, who has been selected to join the Training Program in Integrative Membrane Biology T32! Abby will focus on understanding plasticity in TRP channel expression and function in brain capillaries. Congratulations Abby!

Ashwini becomes an American Heart Association Postdoctoral Fellow!



A huge congratulations to Ashwini, who has been awarded a Postdoctoral Fellowship from the American Heart Association! Ashwini will use the funds to explore the mechanisms of pericyte control of blood flow in health and in Alzheimer's disease. Well done Ashwini!

Nick Weir joins the lab

Tom receives the NIH Director's

New Innovator Award!


At long last, we are delighted to have Nick Weir join the lab, after multiple set back to travel plans imposed by COVID-19. Nick brings expertise in neurophysiology and a number of big data techniques including mass spectrometry and transcriptomic approaches.

Welcome Nick!

Amy passes her qualifying exams



Congratulations to Amy on passing her qualifying exams and advancing to PhD candidacy in the Program in Neuroscience. We are thrilled by the great strides you are making we are all excited to see how your project will develop over the coming years. Congratulations!!


Tom is honored to receive the NIH Directors New Innovator Award to support the lab's work on the role of the vasculature in brain plasticity. The lab is currently hiring at the postdoctoral level for this project, details can be found here. You can read more about the award here and here.

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New publication in collaboration with the Mulkey lab


Beautiful work led by Colin Cleary in the Mulkey lab reveals that P2Y2 receptors in the retrotrapezoid nucleus are key determinants of respiratory chemoreception. More on this work can be found here.

The lab receives its first R01 from the NIA!


We are delighted to have been awarded an R01 from the National Institute on Aging to study the role of pericytes in the control of brain blood flow, and the disruption of this control in Alzheimer's disease.

Liuruimin (Amy) Xiang joins the lab


We are happy to be joined by Amy Xiang as a rotating PIN graduate student! Amy is interested in electrophysiological approaches and will spend her rotation learning to patch native smooth muscle and endothelial cells from the brain.

New publication in Current Topics in Membranes


We are delighted to have the first publication from the lab enter print. In this chapter, we focus on the ion channel genes expressed by brain capillary endothelial cells and explore their potential functional implications in the regulation of brain blood flow. It can be accessed here.

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Ashwini Hariharan joins the lab


We are very excited to be joined by Ashwini Hariharan from the University of Otego in New Zealand. Ashwini's expertise covers neurovascular coupling, endothelial biology, and Alzheimer's disease.

Welcome Ashwini!

Two students join the lab


We are excited to be joined by Colin Robertson, a rotating PIN graduate student who will learn in vivo multiphoton imaging, and Joshua Choi, a JHU student who plans to focus on patch clamp electrophysiology.


Welcome Colin and Joshua! 

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