We are building a group of like-minded scientists who are passionate about understanding the complexities of the brain. We focus on understanding multiple aspects of brain physiology, from the biological mechanisms that regulate how blood flows throughout the brain in health and in disease, to the mechanisms by which cerebrospinal fluid flows and contributes to brain cleaning. The lab is located in the department of physiology at the University of Maryland Baltimore School of Medicine. We are currently looking to hire passionate, talented students and postdocs. If you are interested in learning more and potentially working with us, please use the contact form to get in touch!
Tom Longden, PhD
I received both my B.Sc with honors and my PhD in Pharmacology from the University of Manchester in the UK, and I then completed my postdoctoral training under Mark Nelson at the University of Vermont. I am passionate about ion channels, GPCRs, cerebral blood flow, and I am fascinated by pericytes. When I am not in the lab peering into a microscope, I am usually walking my dog or reading. My aim is to build a nurturing environment in which scientists can develop their ideas and contribute answers to some of the big questions in cardiovascular biology and neuroscience.
Ashwini Hariharan, PhD
American Heart Association Postdoctoral Fellow
I grew up in Mumbai, India where I received my bachelor’s degree in Pharmaceutical Sciences followed by a master’s degree in Pharmacology and Toxicology. I recently graduated with a PhD in Anatomy from the University of Otago in Dunedin, New Zealand; my doctoral research focused on the implications of endothelial nitric oxide synthase deficiency for Alzheimer’s disease. I am interested in exploring the intricacies of cerebrovascular function, especially in relation to neurodegeneration. Besides science, I enjoy reading and traveling.
I received my B.Sc (Pharmacology and Physiology), M.Sc (Neuropharmacology) and PhD (Biomedical Engineering) from Nottingham Trent University, UK. My doctoral research focused on generating and characterising cortical organoids using mass spectrometry and transcriptomic techniques. I recently started my postdoctoral training with the Longden lab and am interested in learning new techniques and exploring mechanisms of vascular plasticity within the brain. In my free time, I enjoy cooking, exercise and board games.
Liuruimin (Amy) Xiang
Graduate Student, Program in Neuroscience
I originally came from Guangzhou, China and I earned my BA in neuroscience from Wesleyan College in Macon, Georgia. During my college years, I started learning patch clamp and picked up a passion for ion channels. Currently, I am fascinated by different types of ion channels in different vascular cells and how they contribute to controlling blood flow. In my free time, I enjoy sports and gaming. If I am not sitting in front of the patch rig, then I may be playing badminton in the gym.
Graduate Student, Program in Neuroscience
I received a double B.S./B.A. in neuroscience and psychology from Brandeis University. I have worked in labs studying sleep and circadian rhythms in Drosophila melanogaster and chronic stress response in rats, both at the University of Pennsylvania. I am interested in the role neurovascular coupling plays in various processes such as learning and memory and the stress response. Outside of lab, I write and play music, consume pop culture content, and spend quality time with my cat.
Rotating Graduate Student, Program in Molecular Medicine
I received by B.S. in Biological Sciences from York College of PA before moving on to the NIH for a postbac fellowship where I worked on modeling COPA Syndrome in C. elegans. My research interests range broadly but include CRISPR as both a therapeutic and reverse genetic tool, and functional characterization of rare genetic diseases. As part of the Molecular Medicine program, I am using my rotations to expand my research experience into neurobiology and advanced imaging techniques. Outside of the lab you can find me relaxing with my two cats, exploring new places to eat, or traveling.
Rotating Graduate Student, Program in Neuroscience
I was born and raised in the Baltimore area. I earned a BS in Biochemistry from the University of Maryland, College Park and gained plentiful research experience in microbiology, cell biology, and virology. I also spent a year working in biopharma manufacturing before joining the Longden Lab in May 2021. In my spare time, I watch movies and podcast about them, cook, watch tons of baseball and football, and enjoy spending time with my dog.