A map of pericyte ion channels and GPCRs
Hariharan A, Weir N, Robertson C, He L, Betsholtz C, Longden T (2020) "The Ion Channel and GPCR Toolkit of Brain Capillary Pericytes."
Frontiers in Cellular Neuroscience 14:601324. doi: 10.3389/fncel.2020.601324
In collaboration with the Betsholtz group at Uppsala University, this paper systematically explores the ion channels and G protein coupled receptors that are expressed at the mRNA level by brain capillary pericytes, and examines what is currently known of their function, with the aim of providing a roadmap to guide further studies of brain pericyte functions and contributions to blood flow control. In particular, we put forth a model for how pericyte KATP channels may play an critical role in controlling brain blood flow.
Hariharan A, Weir N, Robertson C, He L, Betsholtz C, Longden T (2020) “The ion channel and GPCR signaling toolkit of CNS pericytes” Frontiers in Cellular Neuroscience. 14: 601324.
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